(*these authors contributed equally, †corresponding author, Johnson Lab members are underlined)
Johnson Lab Publications
Xiao X, Le HH, Lee MT, Lamm D, Johnson EL†, and Brito IE†. Prevotella copri variants among a single host diverge in sphingolipid production. mBio (2024). https://doi.org/10.1128/mbio.02409-23
Mitchell SB, Thorn TL, Lee MT, Kim Y, Comrie JMC, Bai S, Johnson EL, Aydemir TB. Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism. APS Gastrointestinal and Liver Physiology (2023). https://doi.org/10.1152/ajpgi.00091.2023
Sibinga NA, Lee MT, Buchon N, Johnson EL, Selvaraj V, Marquis H. Do antimicrobial peptide levels alter performance of insect-based aquaculture feeds - a study using genetic models of insect immune activation. Journal of Insects as Food and Feed (2023). https://doi.org/10.3920/JIFF2022.0132
Le HH*, Lee MT*, Besler K, Comrie JMC, Johnson EL†. Characterization of the interaction of dietary cholesterol with the murine and human gut microbiome. Nature Microbiology (2022). https://doi.org/10.1038/s41564-022-01195-9
Lee MT*, Le HH*, Besler K*, Johnson EL†. Characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron. Journal of Lipid Research (2022). https://doi.org/10.1016/j.jlr.2022.100236
Le HH*, Lee MT*, Besler K, Johnson EL†. Host hepatic metabolism is modulated by gut microbiome derived sphingolipids. Cell Host & Microbe (2022). https://doi.org/10.1016/j.chom.2022.05.002
Heaver SL, Le HH, Teng P, Baslé A, Mirretta Barone C, Vu D, Waters J, Marles-Wright J, Johnson EL, Campopiano DJ, Ley RE. Characterization of inositol lipid metabolism in gut-associated Bacteroidetes. Nature Microbiology (2022) 7, 986 - 1000. https://doi.org/10.1038/s41564-022-01152-6
Sibinga NA, Lee MT, Johnson EL, Selvaraj V, Marquis H. Longitudinal samping of the rainbow trout (Oncorhynchus mykiss) microbiome reveals effects of dietary cecropin A and Yersinia ruckeri infection. Frontiers in Marine Science (2022). https://doi.org/10.3389/fmars.2022.901389
Lee, MT, Le HH, and Johnson EL†. A BOSSS method for managing insights into diet-microbiome interactions. Trends in Biochemical Sciences (2021). DOI: doi.org/10.1016/j.tibs.2021.08.004.
Lee, MT, Le, HH, Johnson, EL†. Dietary sphinganine is selectively assimilated by members of the mammalian gut microbiome. Journal of Lipid Research (2020). doi: 10.1194/jlr.RA120000950.
Le HH, Johnson, EL†. (2020) Going Keto? Say βHB-ye Bye to Your Gut Bifidobacteria. Cell Host and Microbe 28:1. doi.org/10.1016/j.chom.2020.06.012.
Postdoctoral Publications
Di Rienzi SC, Johnson EL, Waters JL, Kennedy EA, Jacobson J, Lawrence P, Wang DH, Worgall TS, Brenna JT, Ley RE. The microbiome affects liver sphingolipids and plasma fatty acids in a murine model of the Western diet based on soybean oil. Journal of Nutritional Biochemistry (2021).doi.org/10.1016/j.jnutbio.2021.108808.
Johnson, EL, S. L. Heaver, J. L. Waters, B. I. Kim, A. Bretin, A. L. Goodman, A. T. Gewirtz, T. S. Worgall, and R. E. Ley. 2020. Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. Nature Communications 11: 2471. doi.org/10.1038/s41467-020-16274-w.
Heaver SL, Johnson EL, Ley RE. (2018) Sphingolipids in host-microbial interactions. Curr Opin Microbiol. doi.org/10.1016/j.mib.2017.12.011.
Johnson EL, Heaver SL, Walters WA, Ley RE. (2016) Microbiome and metabolic disease: revisiting the bacterial phylum Bacteroidetes. Journal of Molecular Medicine. doi.org/doi: 10.1007/s00109-016-1492-2.
Graduate School Publications
Mitra M, Johnson EL, Swamy VS, Nersesian LE, Corney DC, Robinson DG, Taylor DG, Ambrus AM, Jelinek D, Wang W, Batista SL, Coller HA. (2018) Alternative polyadenylation factors link cell cycle to migration. Genome Biology. doi.org/10.1186/s13059-018-1551-9.
Lee HN, Mitra M, Bosompra O, Corney DC, Johnson EL, Rashed N, Ho LD, Coller HA. (2018) RECK isoforms have opposing effects on cell migration. Molecular Biology of the Cell. doi:10.1091/mbc.E17-12-0708.
Johnson EL, Robinson DG, Coller HA. (2017) Widespread changes in mRNA stability contribute to quiescence-specific gene expression patterns in a fibroblast model of quiescence. BMC Genomics. doi.org/10.1091/mbc.E17-12-0708.
Suh EJ, Remillard MY, Legesse-Miller A, Johnson EL, Lemons JM, Chapman TR, Forman JJ, Kojima M, Silberman ES, Coller HA. (2012) A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts. Genome Biology. doi.org/10.1186/gb-2012-13-12-r121.
Legesse-Miller A, Raitman I, Haley EM, Liao A, Sun LL, Wang DJ, Krishnan N, Lemons JM, Suh EJ, Johnson EL, Lund BA, Coller HA. (2012) Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity. Molecular Biology of the Cell. doi.org/10.1091/mbc.e12-03-0192.
Wang DJ, Legesse-Miller A, Johnson EL, Coller HA. (2012) Regulation of the let-7a-3 promoter by NF-kappaB. PLoS One. doi.org/10.1371/journal.pone.0031240.
Johnson EL, Suh EJ, Chapman TR, Coller HA. (2012) Identifying functional miRNA targets using overexpression and knockdown methods. Regulatory RNAs. Chapter 12. Springer-Verlag. B.Mallick (eds). doi.org/10.1007/978-3-642-22517-8_12.
Lemons JM, Feng XJ, Bennett BD, Legesse-Miller A, Johnson EL, Raitman I, Pollina EA, Rabitz HA, Rabinowitz JD, Coller HA. (2010) Quiescent fibroblasts exhibit high metabolic activity. PLoS Biol. doi.org/10.1371/journal.pbio.1000514.
Johnson EL, Cunningham TW, Marriner SM, Kovacs JL, Hunt BG, Bhakta DB, Goodisman MA (2009) Resource allocation in a social wasp: effects of breeding system and life cycle on reproductive decisions. Mol Ecol. doi.org/10.1111/j.1365-294X.2009.04240.x.